Death does not make DNA disappear. Long after the heart has stopped and the brain has lost function, genetic material can remain inside cells and tissues. What changes is the environment around it: ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have directly visualized how enzymes find and break DNA molecules in real time. Using high-speed atomic force ...

Metal ions bridging the grooves of two DNA helices explain how they lock together, the first direct look at the DNA zipper ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have directly visualized how enzymes find ...

From 'Why a double helix?', 'What are 5′ and 3′?', to 'Why can it replicate?'—DNAis a molecule that stores information in the ...

Most microscopes can only illuminate objects down to a certain size before tiny features blur together. This blurring is known as the diffraction limit of light. Super-resolution imaging techniques, ...

DNA methylation has become one of the hottest targets in modern biomedicine. The chemical tags that adorn cytosine bases ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

DNA sequence regulates complex reactions and protein-DNA interactions, yet sequence effects remain poorly understood due to the lack of direct, high-throughput approaches to study sequence-dependence ...

The newest DNA sequencing technology from Swiss multinational Roche doesn’t measure DNA directly but in fact analyzes a different polymer altogether. The technology is not yet available for sale, but ...

Schematic showing a single DNA duplex bridging two gold electrodes (yellow) patterned on a silicon nitride substrate (green). The setup allows measurement of electrical conductance as metal ions bind ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...