The inherited mutation substantially increases the chance of developing lung cancer, including in people who don't smoke.

Scientists have identified an inherited genetic mutation that greatly increases the risk of lung cancer, even in people who have never smoked. The mutation involves the EGFR gene, which helps control ...

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study ...

Centromeres in Arabidopsis thaliana evolve through frequent insertions and deletions of repeat units and increased rates of point mutations driven by homology-directed repair, a mutation spectrum that ...

Horizons moderator William Brangham explores more with Robert Kolker. I'm William Brangham and this is "Horizons." Over 55 ...

Deep mutational scanning has transformed the way biologists interrogate proteins, allowing thousands of amino acid substitutions to be tested in parallel and assembled into detailed maps of variant ...

A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals.

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...

Lung cancer is so closely associated with smoking that people who have never smoked may assume their risk is extremely low.

One rare inherited mutation raised lung cancer risk more than smoking did, and the effect was strongest in people who never ...